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Leah Lawrence
Leah Lawrence is a freelance health writer and editor based in Delaware.
Articles by Leah Lawrence
Status Update: MRD Continues to Prove Utility in Hematologic Malignancies
Leah Lawrence
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November 18, 2024
The interest in using quantitative tests to measure residual cancer cells continues to expand in the arena of blood cancers.
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Unpacking CHIP: Recent Updates, Remaining Questions
Leah Lawrence
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October 8, 2024
While research on CHIP has gained momentum in recent years, treating the premalignant condition remains in debate.
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Making Headway in MDS: Two Novel Agents for Advanced Lower-Risk MDS Treatment
Leah Lawrence
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August 26, 2024
Following FDA approval, luspatercept and imetelstat are propelling the MDS treatment landscape forward.
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CAR T-Cell Therapies Remain Worth the Risk
Leah Lawrence
Transplantation & Cellular Therapy
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May 22, 2024
Benefits of CAR T-cell therapy outweigh the hypothetical future risk of secondary malignancies.
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Prognostic Value of CLL-IPI Diminished in Targeted Therapy Era
Leah Lawrence
Chronic Lymphocytic Leukemia
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May 17, 2024
A new evaluation of the CLL-IPI revealed that its impact appears diminished in predicting OS in the era of targeted drugs.
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Epigenetic Signature Could Improve Prediction of MBL Progression
Leah Lawrence
Chronic Lymphocytic Leukemia
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May 17, 2024
The ELCLV3-21 high-risk signature distinguished those with MBL with a high probability of progression.
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T-Bet Suppresses Proliferation of Malignant B Cells in CLL
Leah Lawrence
Chronic Lymphocytic Leukemia
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August 23, 2024
In single-cell resolved multi-omics analyses, T-bet expression in CLL cells correlated with longer overall patient survival.
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What’s Old Is New: Old Technology Finds New Application in Plasma Cell Disorder Management
Leah Lawrence
Myeloma
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February 8, 2024
Researchers are working to define and validate the ways in which mass spectrometry can aid in MM diagnosis and monitoring.
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Why Are Generic Cancer Drugs Out of Reach for Many Patients?
Leah Lawrence
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January 4, 2024
Shortages of essential drugs are not new, with one expert describing it as a “whack-a-mole” problem.
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Molecular IPSS Adds No Prognostic Power for HMA-Treated MDS
Leah Lawrence
Myelodysplastic Syndromes
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December 13, 2023
OS was still inversely proportional to the IPSS-M, but the molecular risk stratification had no additional prognostic power.
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String of Recent Approvals Puts Spotlight on Bispecifics
Leah Lawrence
Transplantation & Cellular Therapy
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February 8, 2024
Here’s what they add to the treatment toolbox for hematologic malignancies.
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How Can We Challenge the Status Quo in Myeloma Research?
Leah Lawrence
Myeloma
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February 8, 2024
Researchers and clinicians are attempting to make clinical trials better reflect the population of patients with MM.
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First-line Selinexor, Ruxolitinib Shows Ongoing Promise for Myelofibrosis
Leah Lawrence
Myelofibrosis
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February 8, 2024
Researchers presented updated data from the phase I XPORT-MF-034 trial at the Eleventh SOHO Annual Meeting.
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Luspatercept Improved Anemia, Transfusion Burden in Myelofibrosis
Leah Lawrence
Myelofibrosis
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February 8, 2024
The open-label ACE-536-MF-001 study included patient cohorts grouped by transfusion dependance and ruxolitinib therapy.
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Pacritinib Spleen Response Yielded OS Benefit in Cytopenic Myelofibrosis
Leah Lawrence
Myelofibrosis
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September 18, 2023
In PERSIST-2, treatment with pacritinib demonstrated a significant SVR benefit compared with the best available therapy, incl
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Event-free Survival at 24 Months in MCL Yielded Expected OS of General Population
Leah Lawrence
Mantle Cell Lymphoma
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September 10, 2023
Achieving event-free survival at 24 months using modern treatments was associated with improved OS.
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Questions Remain About Role of Hypoxia Related to NHL CAR T-cell Therapy
Leah Lawrence
Meeting News
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September 10, 2023
Intratumoral hypoxia could be associated with CAR-T outcomes in patients with non-Hodgkin lymphoma.
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Data on T-cell Exhaustion Support Earlier Use of T-cell-based Therapies in Splenic MZL
Leah Lawrence
Meeting News
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September 10, 2023
The composition of T cells in patients with sMZL may affect the efficacy of T-cell-based therapies.
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Shorter Duration Induction Venetoclax Feasible for Older, Unfit AML
Leah Lawrence
Acute Lymphoblastic Leukemia
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September 6, 2023
This single-center retrospective study looked at outcomes from 18 patients with AML treated with venetoclax plus an HMA.
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T-Cell ALL Overall Survival Differed by Ethnicity, Small Study Showed
Leah Lawrence
Meeting News
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September 6, 2023
The study included 59 patients with T-ALL with a median age of 20 at diagnosis.
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